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How Does Chronic Kidney Disease Affect Creatinine Level?

2014-09-21 09:32| Font Size A A A

How Does Chronic Kidney Disease Affect Creatinine Level?Chronic kidney disease patients are easy to be tortured by high creatinine level which can bring pains and disturb normal life for patients. Well then, how does chronic kidney disease patients affect creatinine levels?

Actually, creatinine is a breakdown product if creatine phosphate in muscle and is usually produced at a fairly constant rate by the body (depending on muscle mass). Also, a part of creatinine come from the meat products we eat.

Chronic kidney disease is a progressive disease which refers to gradual decline of renal function over a period of months or years. It can cause numerous systems’ damage. What’s more, creatinine is an indicator to reflect renal function. Because it is an easily measured byproduct of muscle metabolism that is excreted unchanged by the healthy kidneys. When a person suffer from high creatinine level, it is possible that there is something wrong with his kidneys. Why?

Due to decreased metabolic ability of the kidneys, the harmful and toxic substance in the blood can not discharged out of the body normally, including creatinine, thus high creatinine level will occur. Since the kidneys are damaged by various factors, and the normal kidney tissues are invaded and stimulated by unhealthy factors, leading to kidney lesions. At this time, the glomerular filtration rate will reduce rapidly, and many toxins such as creatinine, urea, etc will pile up in the body. Consequently, high creatinine level appears.

As a matter of fact, in the early stage of kidney disease, patients do not experience high creatinine levels, because our healthy kidneys have strong compensatory ability and half of renal function can guarantee our body health. In other words, high creatinine level is always associated with severe kidney damage which the glomerular filtration rate is less than 50 percentage.

Therefore, you should pay attention to your kidney health if you suffer from high creatinine level. And if you have no idea about how to deal with this condition, please talk with our doctors online directly or email to and we do sincerely hope you can recover as soon as possible.

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