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Home > Understanding Kidney Disease > Kidney Diseases > FSGS > FSGS Treatment >

Are Steroids Effective for Glomerulosclerosis

2019-04-24 16:15| Font Size A A A

Are Steroids Effective for GlomerulosclerosisGlucocorticoids, also known as steroids are the commonly used treatment in kidney disease. But not all patients are sensitive to this treatment. Are steroids effective for glomerulosclerosis? After reading this article, you will find out the answer.

Glucocorticoid therapy can refer to the treatment of minimal change nephropathy, that is, prednisone 1 mg/kg/day, or methylprednisolone 0.8 mg/kg/day, but the duration of maintenance therapy should be prolonged. It is recommended to use 3-4 months as a first-line treatment. If the treatment is ineffective for more than 6 months, it is called glucocorticoid resistance.

If the therapeutic effect of FSGS using steroid alone is not ideal, it should be combined with cyclophosphamide or cyclosporine A. Cyclophosphamide is injected intravenously 0.4-0.6 g each time, and the total dose is not more than 0.1-0.15 g/kg every other week. Cyclosporin A is taken 4-5 mg/kg every day, twice on an empty stomach. Slowly reduce dosage after 2-3 months. It can be maintained at a low dose of 3 mg/kg per day for a long time. The dosage lasts for about half a year.

Tacrolimus 0.05-0.1 mg/kg per day and serum trough concentration 5-10 ng/ml can be used for patients who are ineffective in cyclosporine A treatment.

In patients with glucocorticoid dependence and recurrence, Cyclophosphamide, cyclosporine and mycophenolate mofetil (1-2 g/d, 3-6 months) may be beneficial to prolong the duration of remission.

Alternative treatment to FSGS

If you have tried the above treatment but not get satisfied effect, you can try systemic Chinese medicine treatment. It is Toxin-Removing Treatment. After about one week’s treatment, swelling will fade away. After about half month’s treatment, proteinuria will be reduced greatly. After about one month’s treatment, glomerulosclerosis will be under control. With treatment going on, proteinuria will turn negative, and kidney function will get improved. However, this treatment is not available all over world. If you are interested in it and want to have a try, you have to come to China.

Are steroids effective for glomerulosclerosis? In many cases, simply steroid treatment is not effective for FSGS patients. In such a case, you can try the above systemic Chinese medicine treatment, which can help turn proteinuria negative and give you a permanent control of the disease. For more information on FSGS treatment, please leave a message below or contact online doctor.

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