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Home > Understanding Kidney Disease > Kidney Diseases > Diabetic Nephropathy > Diabetic Nephropathy Basics >

Two Indexes Help You Prevent Diabetes from Developing to Uremia

2018-04-12 14:28| Font Size A A A

Two Indexes Help You Prevent Diabetes from Developing to Uremia
Do not want your diabetes to become uremia? Two indexes are key. Do you know them?

How much do you know about diseases that cause kidney damage?

High blood pressure, diabetes, obesity, urinary tract infections (UTIs), kidney stone, etc.

If you can not control these diseases well for long-term or various indexes can not be kept stable at normal range, they can put extra stress on kidneys so as to cause kidney damage.

Among them, kidney damage caused by diabetes attached more importance. Diabetic Nephropathy is a typical complication of diabetes. The reason why it is paid more attention is mainly that compared with other secondary kidney disease, Diabetic Nephropathy progresses more quickly, and it is one of leading causes of uremia.
Two Indexes Help You Prevent Diabetes from Developing to Uremia

Do all diabetics have kidney damage?

Diabetes is classified into Type 1 Diabetes and Type 2 Diabetes. Most people with Type 1 are younger than 30 years old, and have a sudden onset of illness, which may be closely associated with eating habits, while type 2 diabetes is common in middle-aged or old people, and people with obesity have higher incidence. This kind of disease belongs to normal type.

Diabetic Nephropathy usually occurs in patients with type 2 diabetes. This is usually related with onset age. If it has been over 7 years, attention should be paid to kidney damage. If it has been over 10 years, you should do tests for kidney function every year. Not a few patients have kidney function impairment more or less.
Two Indexes Help You Prevent Diabetes from Developing to Uremia

Patients with over 5 years of diabetes should attach importance to these early signs. They indicate that your kidneys have been damaged.

1. Persistent microalbuminuria, which will develop to massive proteinuria when the disease becomes worse.

2. There are complications associated with retinopathy.

3. Blood urine may present, but only few red blood cells are seen in the sediment.

4. Glomerular Filtration Rate (GFR) usually decreases.

When kidney function becomes impaired, the most concerned problem for Diabetic Nephropathy patients is to control blood sugar level, reduce proteinuria, stop the progression of disease and prevent the coming of uremia.

To reduce blood sugar level, Diabetic Nephropathy patients can choose the following drugs.


It can reduce weight, but long-term application can cause low blood sugar level and increase your risk of lactic acidosis. Therefore, when your kidney disease is in stage 3 or more serious, or when GFR reaches 30 ml/min/1.73m2, you should stop its application, and you had better consult your doctor firstly.


Most insulin is eliminated from body by kidneys. For diabetics with decreased GFR, you should observe your blood sugar level closely when you use insulin in case of low blood sugar level.


The metabolism of pioglitazone is mainly by liver. If you have liver dysfunction with Diabetic Nephropathy, you should adjust its dosage.
Two Indexes Help You Prevent Diabetes from Developing to Uremia

Besides reducing blood glucose level to relieve renal function damage, it is also necessary for you to lower proteinuria. Diabetic Nephropathy patients usually use ACEI to decrease blood sugar level, meanwhile reducing blood pressure and proteinuria to protect kidney function.

If you have any other questions on kidney disease, please leave a message below or contact online doctor.

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