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Home > Understanding Kidney Disease > Kidney Diseases > Diabetic Nephropathy > Diabetic Nephropathy Basics >

Stages of Diabetic Nephropathy

2013-10-06 11:16| Font Size A A A

Do you know what stage of diabetic nephropathy are you in? Many patients have no idea of its stage at all. In order to make the patients to have a comprehensive understanding of their condition, we will talk about the 5 stages of Diabetic Nephropathy (DN).

Stage I

In this stage, the volume of glomerular and renal will increase. Patients may suffer from compensatory renal function hyperfunction. But the kidneys have no pathological change. Their function can be recovered by insulin.

Stage II

Generally, patients in this stage had suffered at least two years’ diabetes. The clinical manifestations are the thickening of glomerular basement membrane, proliferation of mesangial area, and microalbuminuria,

Stage III

Patients in this stage had suffered 10-15 years’ diabetes. This stage, namely early diabetic nephropathy (EDN), is the high-risk period. In this period, the glomerular filtration rate (GFR) would increase, albuminuria would aggravate, hypertension would increase. With effective treatments, it is possible to recover in this stage.

Stage IV

Patients in this stage had suffered 15-25 years’ diabetes. Their urinary albumin excretion rate over 200 micrograms per minute. This stage is also called clinical diabetic nephropathy (CDN). GFR begin to decrease in this period. Most patients would appear hypertension. If the blood pressure were well controlled, the speed of GFR could be slow down.

Stage V

This stage is the final stage of Kidney Failure. Patients would appear persistent proteinuria, glomerular capillary occlusion, low GFR, metabolic waste retention, and hypertension.

Patients should know which stage their conditions belong to. Only with comprehensive knowledge on the disease, can they choose the most suitable treatment. Micro-Chinese Medicine Osmotherapy is recommended to patients with diabetic nephropathy. It has saved thousands of DN patients. If you are interested in this therapy, please email your basic info and medical conditions to and we will give you a reply within 48 hours.

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